Optimal Tolerance Design and Optimization for a Pharmaceutical Quality Characteristic

a benchmarking approach to optimal asset allocation for insurers and pension funds

uncertainty in the financial market will be driven by underlying brownian motions, while the assets are assumed to be general stochastic processes adapted to the filtration of the brownian motions. the goal of this study is to calculate the accumulated wealth in order to optimize the expected terminal value using a suitable utility function. this thesis introduced the lim-wong’s benchmark fun...

Neuro-Optimizer: A New Artificial Intelligent Optimization Tool and Its Application for Robot Optimal Controller Design

The main objective of this paper is to introduce a new intelligent optimization technique that uses a predictioncorrectionstrategy supported by a recurrent neural network for finding a near optimal solution of a givenobjective function. Recently there have been attempts for using artificial neural networks (ANNs) in optimizationproblems and some types of ANNs such as Hopfield network and Boltzm...

Development of a sequential robust-tolerance design model for a destructive quality characteristic

Robust design (RD) and tolerance design (TD) have received much attention from researchers and practitioners for more than two decades, and a number of methodologies for modeling and optimizing the RD and TD processes have been studied. However, there is ample room for improvement. Because most existing research considers RD and TD as separate research fields, the primary objective of this pape...

Optimal design for tolerance and manufacturing allocation

Pharmaceutical “quality by design” approach

10.4103/japtr.JAPTR_343_17 Dear Friends, Based on quality risk management, the pharmaceutical quality by design (QbD) has been emerged as a logical methodology for the development which commences with prior delineated goals and accentuates better understanding of product and process control. The basis of QbD strategy is International Conference on Harmonization guidelines. QbD approach is surfa...